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Emcee:  scaram(o)uche Type:  Moderated
CD123-related abstract (preclinical) coming up at ASH, so maybe it's time for a thread. DART is a very old concept.... I was one of the first to try it, but the original concept came from Dartmouth and served as the foundation science for Medarex.

MGD006, Servier has right to license for some geographies.....

One more ASH abstract, not from MGNX.......

Pointer to the pipeline chart, website.....

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63Not very much, but every bit of info is step forward. Normally, point is can thiMiljenko Zuanic-September 19
62PD1/LAG3: >>Tumor LAG-3 expression is associated with response to combinatuck-September 19
61< MGD013 has a prolonged serum half-life and is being developed for the potenMiljenko Zuanic-September 5
60 MGD013: Zuanic-September 5
59Thanks for your thoughts. Have a great long weekend! Cheers, Tucktuck-September 2
58Well, target (CD3xCD123) may be OK, but 4 days cont. infusion/3 days off dosing Miljenko Zuanic-September 1
57MGD006 may just follow CD3xCD19 path. :-( But I don't see anyone with much otuck-September 1
56Hi Tuck, I guess there us room for some CD3xYYY bispecific, but am not sure thaMiljenko Zuanic-September 1
55MGNX was not putting up any of the development costs after IND, so all they losetuck1September 1
54Another one bite the dust, CD3xCD19, Bispecific (including CDMiljenko Zuanic-August 31
53Another PD-1 deal (from china), IF they (MGNX) want to be "competitive on tMiljenko Zuanic-August 18
52Bullish crossover in MACD and Stochastic oscillators. breakout watch over 18.58.hollyhunter-August 5
51>> bought back my August 17.5 puts for a modest profit << Cool.scaram(o)uche-August 4
50FWIW, on the pop of the last couple of days into this morning, I bought back my tuck-August 4
49Thanks for the chatter guys. I have nothing to add, except that the pipeline isscaram(o)uche-August 3
48The point is to do this ahead of P1 results (early), from competitive landscape tuck-August 3
47<I think it is worth waiting for the next year of data to come in before ratiMiljenko Zuanic-August 3
46The lowest dose with full potential for antitumor activity was 2 mg/kg Q3W Yes, tuck-August 3
45Keytruda: <Mechanism-based translational models with a focus on intratumor exMiljenko Zuanic-August 3
44EARLY, I WAS HOPING THAT PIPELINE WILL BRING FRUIT. Today, they should terminatMiljenko Zuanic1August 3
43MGA1012 (and other DART): This is 3X to 5X Opd/Key dose/regime! What the facxx tuck-August 3
42They are spending $~45M on R&D + G&A, so by now they should show some &qMiljenko Zuanic-August 2
41I think that is is about time to move pass DART hype & nonsense, and do someMiljenko Zuanic-August 2
40My mistake, there was data on 010 presented some weeks ago at EULAR, and it was tuck-August 2
39fwiw, I am very tempted at these levels. I have had two nice trips from 15 to 2mopgcw-August 2
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