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Technology Stocks : MGNX -- MacroGenics
MGNX 17.05+1.0%4:00 PM EDTNews

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To: tuck who wrote (55)9/1/2017 6:15:55 PM
From: Miljenko Zuanic  Read Replies (2) of 63
 
Hi Tuck,

I guess there us room for some CD3xYYY bispecific, but am not sure that DART is right choice??? Roche is leading here, I think. REGN is trying (and some others), but tox profile continut to be problem
For DART, complex continuous iv-dosing, and than that toxicity.....

MGD006 may just follow CD3xCD19 path. :-(

My bets are on bispecific antiPD1xLAG3 (from the animal preclinical results), but this is still DART.... with improved profile, so every 3W dosing at 10-15 mg/Kg ....well, just may be right molecule.

Best, Miljenko
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