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Technology Stocks : MGNX -- MacroGenics
MGNX 17.05+1.0%4:00 PM EDTNews

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To: Miljenko Zuanic who wrote (42)8/3/2017 1:55:49 AM
From: tuck  Read Replies (2) of 63
 
MGA1012 (and other DART): This is 3X to 5X Opd/Key dose/regime! What the facxx they are thinking?


Actually, phase 1 pembro dose went that high. Compare for yourself:

Phase I Study of Pembrolizumab (MK-3475; Anti-PD-1 Monoclonal Antibody) in Patients With Advanced Solid Tumors

A Phase 1 Study of MGA012 in Patients With Advanced Solid Tumors

They are spending $~45M on R&D + G&A, so by now they should show some "meat" not only "bones"!


A large chunk of the R&D spend goes to the P3 program for a drug that I don't think any of us have high hopes for, so I agree with you there. You seemed more constructive on this a few months ago, and things are progressing at the expected pace since then, so what's changed for you?

Cheers, Tuck
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